Articles in Healthspan

Mitohormesis: How Mitochondria Protect Themselves from Oxidative Stress

Mitohormesis: How Mitochondria Protect Themselves from Oxidative Stress

In this article, we’re going to learn about mitohormesis, the activity of reactive oxygen species (ROS) as signaling molecules, and how and why ROS can be both beneficial and harmful. We will also discuss what leads to excessive ROS production and accumulation, how this associates with aging, and where antioxidants fit into the equation. Lastly, we’ll discuss nutritional strategies that can support the antioxidant defenses cells and mitochondria use to protect themselves against excessive ROS.

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What Is Insulin? Understanding The Role of Insulin in Metabolism and Healthy Aging

What Is Insulin? Understanding The Role of Insulin in Metabolism and Healthy Aging

Insulin is a hormone produced by beta cells in the pancreas with a central role in the regulation of metabolism and cell energy reserves. The major metabolic action of insulin is to regulate blood glucose levels and to promote the storage of energy substrates as macromolecules that can be mobilized between meals or in contexts of high energy demand.

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Senescence in Skin Aging — How Qualia Senolytic May Support Skin Youthfulness

Senescence in Skin Aging — How Qualia Senolytic May Support Skin Youthfulness

Cellular senescence is a state of irreversible growth arrest that turns functional cells into zombie cells. These senescent cells occur in all types of tissues and organs and the skin is no exception.

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How Does the Immune System Work? Part 1: An Exploration of the Functions, Responses, and Processes of the Innate Immune System

How Does the Immune System Work? Part 1: An Exploration of the Functions, Responses, and Processes of the Innate Immune System

The immune system is the collection of cells, tissues, and molecules that work together to recognize the healthy cells that make up the body, and protect us against the unfamiliar or damaged. 

The immune system monitors our body continuously searching for certain categories of things that may threaten our health: infectious microbes, viruses, fungi, and parasites (i.e., germs or pathogens); toxic cellular products; and damaged or diseased cells, including senescent or tumor cells.

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The Formulator's View of the Qualia Senolytic Ingredients

The Formulator's View of the Qualia Senolytic Ingredients

Improve your health and extend your lifespan with Qualia Senolytic, a dietary supplement designed to promote the removal of senescent cells

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Neurohacker’s Guide to Hand Washing as an Antiviral Strategy

Neurohacker’s Guide to Hand Washing as an Antiviral Strategy

One of the public health goals of prevention is “flattening the epidemic curve*,” which essentially means decreasing the growth of new infections now, so they can be spread out over time. This is the reason why businesses are asking employees to work from home and governments are enacting policies to support social distancing strategies. In essence, public health wants to push some of the infections that might otherwise occur in the next weeks to sometime in the future … the further into the future the better.

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Can Gargling Prevent Upper Respiratory Tract Infections?

Can Gargling Prevent Upper Respiratory Tract Infections?

There’s no data suggesting that gargling prevents infection from the virus causing COVID-19. The SARS-CoV-2 virus is too new to know. But, in general, gargling might have modest preventive benefit for colds (and likely less so for the flu). Once someone has an upper respiratory infection, gargling is not a treatment for the infection. It would, at best, offer some degree of soothing of sore throat symptoms.

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The Formulator's View of the Qualia NAD+ Ingredients

The Formulator's View of the Qualia NAD+ Ingredients

Qualia NAD+ is designed to provide support for optimizing NAD+ levels in adults, regardless of age. Here's an in-depth look at the ingredients we chose for the formulation.

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What Years of Being Obsessed With Mitochondrial Health Taught Me About Blue Light: A Q+A With Matt Maruca

What Years of Being Obsessed With Mitochondrial Health Taught Me About Blue Light: A Q+A With Matt Maruca

Matt Maruca, CEO of Ra Optics, shares with us how light drives mitochondrial functions, the science behind blue light blocking glasses triggering melatonin secretion, explores the eye/brain connection, and gives us the 411 on blue light blocking glasses (spoiler alert: they’re not all created equal).

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What is Mitochondrial Biogenesis? Benefits & Effects

What is Mitochondrial Biogenesis? Benefits & Effects

Similar to many other cellular processes, the creation of new mitochondria (a process called mitochondrial biogenesis), and the interacting pathways that influence it, suffers with aging. This is the bad news. The good news is that there are things we can do to better support maintaining a fitter mitochondrial network.

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What is Glycolysis? Where Glycolysis Takes Place, Definition, and Steps of the Glycolysis Pathway.

What is Glycolysis? Where Glycolysis Takes Place, Definition, and Steps of the Glycolysis Pathway.

Glycolysis is the metabolic pathway that breaks down the carbohydrate glucose to produce cell energy in the form of ATP. Glycolysis generates ATP directly, as a product of the pathway’s chemical reactions, and indirectly, using energy generated by electrons extracted from the chemical bonds of glucose. In the human body, glucose is the preferred fuel for the vast majority of cells.

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NAD: Introduction to an Important Healthspan Molecule

NAD: Introduction to an Important Healthspan Molecule

In this article we’ll be covering the “big picture” when it comes to NAD. We’ll be doing a deeper dive on specific topics we introduce in this article in subsequent articles in this series. As you go through this series of articles please keep in mind that, like other molecules in the body, NAD+ is a means to an end. We don’t care about NAD+ on its own; we care about it because of what it allows cells to do. 

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What Is Oxidative Phosphorylation?

What Is Oxidative Phosphorylation?

Oxidative phosphorylation (OXPHOS) is the major pathway of ATP production. ATP is the energy-rich molecule that powers cellular processes that require energy input. OXPHOS occurs in mitochondria and uses energy extracted in the metabolism of cellular fuels, particularly in glycolysis, fatty acid oxidation, and the citric acid cycle, to power the production of ATP.

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12 Ways To Upgrade Your Lifespan & Healthspan IQ

12 Ways To Upgrade Your Lifespan & Healthspan IQ

The amount of time we live is called lifespan. The length of time that a person is healthy and functional—not just alive—is called healthspan. Scientific understanding in these areas is advancing rapidly. Below are 12 things the collective thinks will help on your journey to a longer healthier you. 

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Qualia Immune - The Science Behind The Formula & Immune System Intelligence

Qualia Immune - The Science Behind The Formula & Immune System Intelligence

Qualia Immune combines 19 carefully selected ingredients for premium immune support. We think of it as being training for the immune system; a formulation designed to challenge the immune system in ways that will help it be fitter and perform more intelligently. 

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The Formulator's View of the Qualia Immune Ingredients

The Formulator's View of the Qualia Immune Ingredients

Neurohacker Collective developed Qualia Immune, because we think that having a smarter, fitter, higher-performing immune system is a foundational pillar of health. But how does one go about accomplishing this?

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The 9 Hallmarks of Aging

The 9 Hallmarks of Aging

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Qualia Senolytic Pilot Study

Qualia Senolytic Pilot Study

During the development of Qualia Senolytic, Neurohacker Collective put our newest healthy aging product to the test to find out how users would respond. 

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