Collective Insights Blog

NAD+ Consumption Uses: An Overview

NAD+ Consumption Uses: An Overview

The NAD+ form of the molecule is required for certain cellular signaling reactions that change the way cells behave. Unlike redox, where the molecule is conserved, the NAD+ molecule is broken apart or “consumed” when used for signaling. It’s these NAD+ consumption uses that have been a main reason for the resurgence of scientific interest in strategies to boost NAD+.

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Qualia Life: Putting the Healthy Aging Puzzle Together

Qualia Life: Putting the Healthy Aging Puzzle Together

We all age. But, we don’t all age at the same rate. From a bottom-up point of view, we are a complex colony of tens of trillions of individual cells. We care about what healthier cells allows the body to do better. Qualia Life is our solution to cell support for better aging. 

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Benefits of Gynostemma pentaphyllum Whole Herb Extract

Benefits of Gynostemma pentaphyllum Whole Herb Extract

Gynostemma pentaphyllum (Southern Ginseng) is an herb attributed with having ginseng status. Until fairly recently Gynostemma pentaphyllum was used primarily in mountainous regions of southern China and northern Vietnam. It’s been described as the "immortality herb,” because people within Guizhou Province, where herbal teas made from the plant are consumed regularly, are said to have a history of unusual longevity. 

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There's Nothing Funny or Interesting about Perfection

There's Nothing Funny or Interesting about Perfection

I was recently interviewed for the PureJoy podcast.  We talked about all the things they cover on that podcast; health, wellbeing, our products, and human optimization.  It was all things I'm very interested in both professionally and personally.  Towards the end of the recording Elaina Love, the host, asked me a great question, (paraphrasing)  "What are you working on perfecting about yourself now?

I paused for a moment to think about my answer and what areas of my life I'm working on and perfecting and it hit me.

Not being so damn perfect

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The Stories We Tell, Part 1.

The Stories We Tell, Part 1.

There’s an old quote by Mark Twain that goes

I Am an Old Man and Have Known a Great Many Troubles, But Most of Them Never Happened

This quote is probably misattributed to Twain as there is much speculation about who actually said it first ranging from Thomas Jefferson to English author Martin Farquhar Tupper, Seneca, Winston Churchill, James A. Garfield, and more.

The source of the quote doesn’t matter.  Its truth resonates as it was probably thought, written and spoken by many men throughout history in slightly different forms.

The point of the quote is we do not live in reality.  We live our lives in the stories we tell.

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You Have Less Than 100 Days Left...

You Have Less Than 100 Days Left...

You have less than a hundred days until the end of the year.  Or maybe less, depending on when you are reading this.

Of course it’s all arbitrary.  The end of the year or the beginning of the next is just a day like any other.  But as the time passes and we see and set dates for our goals and dreams, we are reminded of the work we want to do and the world we wish to create for ourselves.

What are your goals for the next 100 days?

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What is elevATP® Ancient Peat and Apple Fruit Extract?

What is elevATP® Ancient Peat and Apple Fruit Extract?

ElevATP® is a proprietary, clinically researched combination of a water extract of “ancient peat” (fossilized plants) and apple extract. The ancient peat contains 70 elements and is especially rich in carbon, magnesium, nitrogen, oxygen, and sulfur. ElevATP® is a clinically tested product with human studies for sports performance, body composition, and elevating ATP.

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Benefits of Strawberry Seed Extract

Benefits of Strawberry Seed Extract

Strawberries are a good source of polyphenols. The seeds are an even better source. We made sure to source an extract standardized for at least 2% polyphenols. Studies of this extract suggest it might support healthy skin, weight, metabolism, and other functions needed for healthy aging.* Strawberry polyphenols would also be expected to support antioxidant defenses and overall cellular health.* But the main reason we included the strawberry seed extract is because it is a source of a specific flavonoid called tiliroside.

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Citrus sinensis L. Fruit Extract: Sources and Benefits

Citrus sinensis L. Fruit Extract: Sources and Benefits

Citrus × sinensis is the group of oranges that includes the commonly eaten navel orange and the blood orange. The peels and fruit are a rich source of citrus bioflavonoids. But our interest went beyond just including a generic citrus bioflavonoid mixture. What we were really interested in is a specific polymethoxylated flavone called nobiletin. Nobiletin has been identified as clock-enhancing small molecule, so is a key nutrient to support body clock functions.

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Sophorae japonica L. Flower Extract: Sources and Benefits

Sophorae japonica L. Flower Extract: Sources and Benefits

Rutin is a type of polyphenol called a flavonoid glycoside. It’s composed of quercetin and the disaccharide rutinose. It’s also called rutoside, quercetin-3-O-rutinoside and sophorin. While it’s found in a wide variety of plants, including citrus, foods with the highest concentrations of rutin include capers, black olives, buckwheat, and asparagus. The most common use of rutin has been for supporting healthy veins. But it does much more.

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Citrus grandis Fruit Extract: Sources And Benefits

Citrus grandis Fruit Extract: Sources And Benefits

Apigenin belongs to the flavone class of polyphenol compounds. It is one of the more common flavones in the diet, found in many fruits and vegetables, including celery and parsley. It’s also found in high amounts in the flowers used to make chamomile tea.

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Calcium β-Hydroxy-β-Methylbutyrate (HMB): Sources And Benefits

Calcium β-Hydroxy-β-Methylbutyrate (HMB): Sources And Benefits

β-Hydroxy-β-Methylbutyrate (HMB) is a metabolite of l-leucine (an essential amino acid). As we get older, muscle size, strength, and performance decline. This can occur even if we continue to exercise. HMB has been used as an ergogenic substance (i.e., something that supports improved sports performance) for more than 20 years, with most of the research focused on supporting muscle performance and helping muscles age better. 

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Rosmarinus officinalis Leaf Extract: Sources And Benefits

Rosmarinus officinalis Leaf Extract: Sources And Benefits

Rosemary is a member of the mint family. Its common name derives from Latin and translates as “dew of the sea,” because it thrives close to the coast in dryer areas throughout the Mediterranean. It was used as a spice and folk medicine by Egyptians, Greeks, and Latin cultures. While rosemary contains a range of health-supporting polyphenols, including carnosol, carnosic acid, and rosmarinic acid, our main interest was in a triterpene in rosemary called ursolic acid, which supports muscle performance.

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Sirtmax® Kaempferia parviflora Root Extract: Sources And Benefits

Sirtmax® Kaempferia parviflora Root Extract: Sources And Benefits

Kaempferia parviflora is found in the upper northeastern regions of Thailand. It is commonly called black ginger, because of the intense purple-black color and similar shape of the roots to ginger. The traditional use has been as a health tonic and energy enhancer leading to it sometimes being called “Thai ginseng.” The novel active constituents are polymethoxyflavonoids polyphenols. 

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Theobroma cacao Seed Extract: Sources And Benefits

Theobroma cacao Seed Extract: Sources And Benefits

Theobroma cacao can be translated as chocolate, food of the gods. This tree is native to the tropical regions of the Americas. The beans are the source of the cocoa used to make chocolate. But this extract is more than simply a pleasure for our tastebuds. Over the past decade chocolate has had a blossoming reputation as being heart healthy. As it turns out, it might also be good for our mitochondrial structure and function.

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What is Vitamin K2? An Exploration of its Benefits

What is Vitamin K2? An Exploration of its Benefits

Vitamin K is a family of structurally similar, fat-soluble vitamins. The two main members of the family are vitamin K1 and K2. Our interest in vitamin K was prompted when looking for compounds that might be able to rescue mitochondrial performance. This led us to source vitamin K2, ultimately as MK-7. 


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Benefits of Niacin & Niacinamide

Benefits of Niacin & Niacinamide

The main role of vitamin B3 is to make NAD molecules. This is important because the NAD molecule sits at the crossroads of mitochondrial energy production (i.e., ATP), cellular repair and signaling, and cellular defenses. Unfortunately, NAD+ levels decrease with age. This is the bad news. The good news is that there are strategies that can be used to make more NAD+. One of these is vitamin B3.

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L-Tryptophan: Sources and Benefits

L-Tryptophan: Sources and Benefits

L-tryptophan is an essential amino acid. This means the body cannot synthesize it: it must be obtained from the diet. It’s been known for decades that L-tryptophan has niacin equivalent activity in the body (i.e., we can make NAD+ molecules from it). L-tryptophan is unique because it’s the only way to build NAD+ that doesn’t start from vitamin B3. It does this by a de novo synthesis pathway, which creates a niacin molecule through a series of biological reactions. So, L-tryptophan’s inclusion would seem to be a natural fit in a formulation that wants to support boosting NAD+

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French Red Grapes Extract: Sources and Benefits

French Red Grapes Extract: Sources and Benefits

BioVin® is a premium quality grape extract made from the juice, seeds, and skins of red grapes grown in France. It's rich in both trans-resveratrol and grape polyphenols.

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Cinnamon: Sources and Benefits

Cinnamon: Sources and Benefits

Cinnamon is one of the world's oldest spices. Along with pepper and ginger, it was a big part of the spice trade between Asia and Europe. Cinnamon trees are native to India, Sri Lanka, Indonesia, and Burma. What we think of as cinnamon comes from the inner bark of several different tree species from the genus Cinnamomum. 

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Ashwagandha: Sources and Benefits

Ashwagandha: Sources and Benefits

Ashwagandha is an Ayurvedic herb often referred to as “Indian ginseng.” Within this system of it was classified as a general tonic and strength promoting. Its uses included infusing energy and vigor in circumstances characterized by exhaustion or a lack of physical energy. 

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Polyphenols: Sources and Benefits

Polyphenols: Sources and Benefits

Dietary polyphenols are a family of plant compounds found in common foods including fruits, vegetables, nuts, chocolate, coffee, and tea. These compounds play important roles in the plant kingdom, protecting plants from infections, pests, UV irradiation from the sun, oxidative stress, and toxic metals and chemicals.

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Online Education: An Exploration of 7 Websites to Fuel Your Mind

Online Education: An Exploration of 7 Websites to Fuel Your Mind

Get ready to fuel your mind with seven of our favorite resources in the form of websites, companies, programs and even apps that should be on your neurohacking radar!

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How is NAD+ Made? Salvage Pathway

How is NAD+ Made? Salvage Pathway

The salvage pathway is used to produce NAD+ from nicotinamide molecules. Whether the source of the nicotinamide is vitamin B3 (as niacinamide), newer nicotinamides (e.g., nicotinamide riboside [NR], nicotinamide mononucleotide [NMN]), or molecules in food that get broken down during digestion into nicotinamide, the salvage pathway turns them into NAD+ in our tissues.

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Nootropics for Energy: How Athletes Use Smart Drugs as Ergogenics

Nootropics for Energy: How Athletes Use Smart Drugs as Ergogenics

In our last article, Nootropics for Athletes, we discussed several ergogenics (a category of supplements that enhance physical performance, stamina, or recovery) and how they can also be used to optimize brain energy and mental performance. Many of those substances, such as creatine, were well-researched because of their effects on the body. The same is true for numerous nootropic supplements, which were designed to optimize mental performance.

In this article we will cover some well-studied nootropics that also have physical enhancing effects. 

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