Echinacea purpurea Root Extract


Echinacea | Purple coneflower | Echinaceae purpureae radix


  • Supports general immune health*
  • Supports upper respiratory health*


Echinacea purpurea is a flowering plant native to North America. It is one of several species of Echinacea used as a dietary supplement—others include E. angustifolia and E. pallida. E. purpurea was used by Native Americans for a variety of purposes, but it’s reputation as an immune tonic date to the Eclectics (specialists in botanicals from the late 1800’s). This reputation has endured: E. purpurea is one of the most widely used herbal immune tonics. The roots, flowering tops, or combinations of both can be used. We consider the roots as a better choice for long-term use. E. purpurea root extracts support an overall healthy immune system, essentially acting as an immune adaptogen. While the roots have a number of compounds[1,2], the complex arabinogalactan polysaccharides support innate immune cells in ways that are consistent with trained immunity. This means that root extracts provide a challenge for immune cells, which adapt to become fitter and more efficient.*


Echinacea purpurea Root Extract is a 4:1 extract made from selected roots.

Echinacea purpurea Root Extract is non-GMO, gluten-free, and vegan.


Echinacea purpurea roots have been used as herbal immune tonics, with the dose used vary depending on the type of extract. For 4:1 extracts the established daily adult dose range is 150-300 mg[3]. We consider Echinacea purpurea Root Extract to follow hormetic principles similar to herbal adaptogens (see Neurohacker Dosing Principles). Herbal adaptogens tend to have a hormetic zone (or range) where there’s a favorable biological response, so it’s important to dose Echinacea purpurea Root Extract within the established dose range. Our dosage is consistent with this established dosage range.



  • Supports general immune health[4–13]
  • Supports post-exercise immunity[5,10]
  • Supports innate immunity[4,14–23]
  • Supports adaptive immunity[5,16,24–28]
  • Supports cellular intrinsic immune defenses[29–33]
  • Supports mucosal immunity[5,27]
  • Supports immune tolerance[11,14]
  • Supports immune signaling[16,18,24,27,29,31,33–36]
  • Supports the hematopoietic stem cells that produce immune cells[13,14,21,23]
  • Supports healthy dendritic cell function[17,18,20,22]
  • Supports healthy natural killer cell function[4,13–16,19,23]
  • Supports healthy T cell function[16,24–27]
  • Supports healthy B cell function[5,27,28]

Gastrointestinal system and gut microbiota

  • Supports the gut microbiota[37]

Healthy aging

  • Daily consumption supports healthspan in mice[23]
  • Supports stem cell function[38]
  • Counters cellular senescence[39]


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