Nicotinamide riboside and nicotinamide mononucleotide are newer (and very expensive) dietary ingredients used to boost NAD+. Boosting NAD+ is not unique to these newer ingredients. It’s the defining characteristic that makes a compound a vitamin B3. The niacin equivalents—niacin (nicotinic acid; NA) and niacinamide (NAM)—boost NAD+. L-tryptophan is also a precursor for NAD+. We included both NA and NAM, as well as L-tryptophan, because these ingredients can be used to make NAD+ and this approach supports three different ways of making it. Redundancy is a core value within complex systems science and something we look for when formulating our products.
From our research we also are not convinced that nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) offer good value or actually deliver on their intended goals. Studies in the 1990’s found that NAD+ and other molecules in our food are broken down into niacinamide before being absorbed. NAD+ in food, as an example, was first broken down into NMN. The NMN was then further broken down into NR. And the NR was slowly turned into NAM during digestion. A small amount of this NAM was turned into NA by gut microbiota. So it was NAM (and to a much lesser extent NA) that was absorbed. Until information exists showing that the NR and NMN molecules can make it past digestion and the liver intact, we think these are very expensive ways to do something the other niacins do.
Neurohacker Collective uses a model of science called complex systems science. One of the core principles is adaptation. Living organisms are experts at adapting to things.
Qualia Life effects are dose-dependent, varying with body weight, general sensitivity and desired level of effect.
The standard dose for most people is 8 capsules. Take Qualia Life first thing in the morning, with food.
How much water should I drink with Qualia Life?
When using the Qualia Life capsules, we recommend drinking a big glass of water (at least 8 ounces) when you take them, and making sure you drink plenty of fluids throughout the day, especially during the first week. One of the ingredients—creatine (as tricreatine malate)—is believed to pull water into cells. Because of this, it’s important to make sure you pay special attention to being and staying hydrated when you first begin to use products with this ingredient.
We haven’t studied Qualia Life in combination with intermittent fasting, so we don’t know whether in the real world it would help or hinder the response to this behavior.
How does Qualia Life work?
We’ve written a series of articles discussing how Qualia Life works in detail. But, in general, it works by helping our cells and mitochondria do more work, especially the types of tasks they tend to struggle to get to as we get older. When our cells and mitochondria can do more work, and get to all the important jobs we need them to do, we look, feel and function better.
A good strategy, when starting anything new, is to start slow and gradually working your way up. This takes advantage of the body’s adaptive capacities and minimizes chances of poor response. Exercise is a great example of this. When starting a new exercise routine, the tendency is to want to do a lot right away. But this increases chances of having very sore muscles or getting injured. So, it’s better to start conservatively and slowly do more as your body gets accustomed to the new routine.
Qualia Life can be taken by any adults, but the groups we had in mind when we formulated and tested it include:
One of the interesting things found in studies is that placebos can have positive effects … and unwanted effects. The common side-effects seen from placebos match what are found in studies of dietary supplements and what we saw in our tolerability testing.
Yes you can take Qualia Life with Qualia Mind, Qualia Focus or Qualia Nootropic Energy.
When we designed Qualia Life, we did so understanding people would take it with one of the other Qualia nootropic products.
What is Eternus?
Eternus was designed to make your cells and mitochondria (the powerhouses of cells) work better. When your cells and mitochondria are able to do their jobs better, we look, feel, and perform better.
Eternus was formulated to comprehensively support the multiple interacting metabolic pathways, signaling processes, and cellular mechanisms of long-term healthy function. Better cells and mitochondrial function translates into more high-performing days and longer healthy years.