Huperzine A
Overview:
Huperzine A is a potent natural synaptic enzyme modulator. Studies indicate its ability to support learning, memory, neuroplasticity, and executive function.
Scientific Name:
Huperzine A extracted from Huperzia serrata
- Acetylcholinesterase inhibitor[1]
- NMDA receptor antagonist[1]
- Neuroprotective against hydrogen peroxide damage, glutamate excitotoxicity, and beta amyloid pigmentation[1]
- Neurogenic through increased proliferation of hippocampal neural stem cells and NGF stimulation[2]
- Upregulates REM sleep (many report increased lucid dreaming)
- Supports memory consolidation and neuroplasticity[1]
- Synergistic with cholinomimetics and cholinosensitizers
More Info:
References
[1] Wang R, et al (2006). Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine. Acta Pharmacol Sin, 27(1):1-26. doi: 10.1111/j.1745-7254.2006.00255.x
[2] Ma T, et al (2013). Huperzine A promotes hippocampal neurogenesis in vitro and in vivo. Brain Res, 1506:35-43. doi: 10.1016/j.brainres.2013.02.026