Toothed Clubmoss | Chinese Club Moss | Huperazon
Supports cholinergic neurotransmission *
Supports brain function and cognitive performance *
Supports neuroprotection *
Huperzia serrata (synonym Lycopodium serratum) is a species of fir clubmoss that has been used in Traditional Chinese Medicine (as Qian Ceng Ta). Huperzia serrata has several bioactive compounds, including lycopodium alkaloids, triterpenes, flavones and phenolic acids. The most important and widely studied of these is the alkaloid huperzine A, which indirectly supports healthy acetylcholine levels in the brain. Acetylcholine is a neurotransmitter and neuromodulator that plays important roles in cognitive function, most notably, in the neural mechanisms of memory [1], but also in executive function, alertness, attention, and learning. Acetylcholine supports different types of memory, from working memory to long-term memory, and different phases of memory, from memory formation to consolidation and retrieval. By supporting acetylcholine signaling, huperzine A supports cognitive function. Huperzine A has also been shown to support brain antioxidant defenses and neuroprotective functions [2,3].*
Huperzia serrata leaf extract is made from the aerial parts of the plant. It is standardized for 1% Huperzine A.
Huperzia serrata leaf extract is non-GMO, gluten-free and vegan.
Persons using huperzine A as a nootropic typically take a dose ranging from 50 to 200 ΞΌg. Neurohacker Collective uses an amount consistent with the lowest end of this range (50 ΞΌg). On Qualia products, the labeled amount (e.g., Huperzia serrata Leaf Extract (1% Huperzine A) is 5 mg ) refers to the amount of the Huperzia serrata Leaf extract not to the amount of huperzine A. Because the extract is standardized for 1% huperzine A, and each miligram of H. serrata leaf extract provides 10 ΞΌg of huperzine A, a 5 mg dose of the extract supplies 50 ΞΌg of huperzine A. We opted for a dose at the low end of the range because we believe huperzine A is additive with other ingredients used in our formulation for supporting brain health.*
Supports brain function and cognition*
Supports memory and learning [4β9]
Supports cognitive health [4β6,8β16]
Supports task switching [15]
Supports long-term potentiation (LTP) [17]
Supports acetylcholine levels [2,4,5,10,18β22]
Supports choline acetyltransferase activity [10β13]
Supports dopamine release [4,19,20,22]
Supports noradrenaline release [4,20,22]
Influences NMDA glutamate receptor activity [4,23β26]
Supports the levels of neurotrophic factors (BDNF, NGF) [27]
Supports hippocampal neurogenesis [28]
Supports neuroprotective functions [3,4,11β13,17,20,21,27,29β35]
Supports brain antioxidant defenses [3,12,30β34,36]
Supports neurovascular health [37]
Supports blood-brain barrier function [37]
Influences neural cytokine signaling [10,37β39]
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.
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