Japanese Pagoda Tree Flowers
Rutin | Rutoside | Sophorin | Quercetin-3-O-Rutinoside
Rutin is a flavonoid glycoside composed of quercetin and the disaccharide rutinose. It’s also called rutoside, quercetin-3-O-rutinoside and sophorin. The name rutin derives from the plant Ruta graveolens (Rue). Historically, rutin has been considered to be part of what was once called vitamin P, but what we now think of as citrus bioflavonoids. While it’s found in a wide variety of plants, including citrus, foods with the highest concentrations of rutin include capers, black olives, buckwheat, and asparagus. The most common use of rutin has been for supporting healthy veins.
Sophorae japonica L. (i.e., Japanese Pagoda Tree) flower extract was selected as an ingredient to provide a standardized amount of rutin. Dried flower buds are used as a starting material to extract rutin, because they can contain as much as 20% rutin.
Many flavonoid molecules are part of plants’ protective responses to mild environmental stress. Consuming them tends to produce adaptive functional responses, upregulating pathways that provide stress resistance. Because of this, we don’t think of flavonols like rutin as being “more is better” ingredients. Instead we think it’s better to use them following hormetic dosing principles (see Neurohacker Dosing Principles). Flavonoids are additive, and often synergistic with other polyphenol compounds, so the combination of all polyphenols in a formulation should be considered when determining dosage (not the amount of a single polyphenol molecule in isolation). For these reasons we use a moderate dose of rutin.
Mitochondrial biogenesis and function
Exercise performance (ergogenic effect)
Protection of other organs and systems
Healthspan /lifespan extension
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.