Getting the Most Out of DL-Phenylalanine (DLPA)

Getting the Most Out of DL-Phenylalanine (DLPA)

One of the biggest factors in living a healthy life is what we eat. Having a balanced diet gives us a better chance at including everything we need for our bodies to function properly. One class of nutrient often lacking in our diet is amino acids. Since amino acids build protein, it’s important that we have enough in our diets. We usually find amino acids in food sources such as beef, eggs, fish, legumes, nuts, and whole grains. Phenylalanine is an essential amino acid.  Sometimes, we do not have enough food that contains phenylalanine in our diet.  Individuals not getting enough essential amino acids should consider taking DL-phenylalanine as a dietary supplement. Dietary supplements can also be known as nutritional supplements.

What is DL-Phenylalanine?

DL-Phenylalanine (DLPA) is an amino acid supplement, a synthetic phenylalanine. Phenylalanine is a neutral,non-polar amino acid that plays a crucial role in many functions within the body. One of those functions is to produce tyrosine, a major component for synthesizing hormones. Phenylalanine also produces neurotransmitters in the body, including epinephrine, dopamine, and norepinephrine. Phenylalanine is a natural amino acid and found in many protein-rich foods. If you’re eating a chicken thigh, drinking milk, or chowing down on scrambled eggs, you’re getting phenylalanine in your diet. 

Phenylalanine is found in three different forms. The natural form, found in food, is also called L-phenylalanine. There’s also a synthetic form, D-phenylalanine, which is very similar to the natural version. Both of these forms come with their own unique benefits, but if you want to get the most out of  them, you’ll want to look at the third form: DL-phenylalanine. This form combines both the “L” and “D” forms, creating a supplement with the benefits of both types.

DL-Phenylalanine Benefits

Since DLPA brings a lot of benefits to the table, it’s worth getting to know what those benefits are. Here are a few that you  should pay close attention to.

Enhancing Your Mood

As noted above, phenylalanine is an important component in the production of neurotransmitters like dopamine and epinephrine. If your body generates more “feel good” hormones, this will have a positive impact on your mood. With DLPA, your body may also produce tyrosine, which  can also increase dopamine production. The more dopamine you have impacting your brain, the more likely you are to experience an overall enhanced mood, reduce pain and have greater feelings of happiness and fulfillment. People with a phenylalanine deficiency may be at risk for lower adrenaline and noradrenaline levels. The amount of phenylalanine you have can be very critical. DLPA may also help to produce more adrenaline and noradrenaline, which can help improve your energy level and motivation to work throughout the day. Taking DLPA may lead to an increased sense of self-worth, and a more positive outlook on life. If you have lower phenylalanine levels it may affect your mood.

Sharpening Your Mind

With more neurotransmitters in your system, you may experience some other important benefits as well. One of those benefits may include having a sharper mind and an increased amount of concentration.  Taking DLPA may also help to reduce brain fog. DLPA can bind to glutamate AMPA receptors in the brain, which sharpens the communication between the brain’s synapses, and results in enhanced memory and improved learning.

Helping With Your Pain

DLPA is also able to block the enkephalinase. This can lead to a relief from certain types of pain. DLPA can also play a big role in producing more opioids naturally within your body, which can also help with pain relief. Therefore, it could be a very beneficial health benefit. Though more research is needed, it’s an exciting possibility and could point to more uses for DLPA in the future. Research suggests that it could be very beneficial for low back pain as well.

Other Benefits

Early research indicates that DLPA could provide other benefits worth investigating. Some research shows that DLPA may be able to help with certain skin conditions like vitiligo. Once again it can be possibly effective. The more research that is done on the potential benefits of DLPA, the more we’ll learn about this supplement and the impact it can have on your life.

Taking DL-Phenylalanine

As always, consult with a doctor when adding DLPA to your supplement regimen. When looking at the most beneficial nootropics, make sure to include DLPA in your study. It’s an effective supplement with health solutions and benefits you won’t want to miss.


  • Eddie Quest
    "TAKING DL-PHENYLALANINE"... Consult someone else. Not much useful information there, guys.
  • Songhope
    Lots of useful info here. I've researched DLPA before and have taken it for a few years. I did not know about the pain connection, though. I'll add it to the list for my sister who's had Rheumatoid Arthritis for 3-4 years now. RA also has an effect on cognition, eventually. The systemic inflammation is the main contributor, so this will have dual benefit.
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