Sea Buckthorn (Hippophae rhamnoides) Fruit Extract

COMMON NAME

Sea Buckthorn | Sea-buckthorn | Sandthorn | Sallowthorn | Seaberry


TOP BENEFITS OF SEA BUCKTHORN FRUIT

Supports skin health *

Supports antioxidant defenses *


WHAT IS SEA BUCKTHORN FRUIT?

Sea buckthorn (Hippophaes rhamnoides) is a shrub native to cold-temperate regions of Europe and Asia, stretching from the West Coast of Europe through Northern Europe, Russia, Tibet, India, China and Mongolia. The botanical name Hippophaes is from the Greek words "Hippo", horse, and "Phaos", to shine, and comes from stories about ancient Greeks feeding sea buckthorn to horses and noticing the horses became healthier and had shinier coats. Legend has it that Genghis Khan used sea buckthorn to keep his army healthy and horses prepared for battle. The fruits are small yellow-orange berries which have a variety of antioxidant compounds. They contain vitamin C, vitamin E (tocopherols), a mixture of carotenoids (α- and β-carotene, zeaxanthin, lutein, lycopene, and β-cryptoxanthin), minerals, and polyphenols, particularly flavonoids. Their combination of nutrients is one of the reasons they have been described as a super fruit. One of the traditional uses of sea buckthorn fruit has been for supporting skin health.*


NEUROHACKER’S SEA BUCKTHORN FRUIT SOURCING

Sea Buckthorn is a fruit extract standardized to contain not less than 5% flavones (flavones are a group of pale yellow flavonoids).

Sea Buckthorn Fruit Extract is non-GMO, gluten-free, and vegan.


SEA BUCKTHORN FRUIT DOSING PRINCIPLES AND RATIONALE

We selected a Sea Buckthorn fruit extract, which provides a standardized dose of flavones (a type of flavonoid). Flavonoids tend to follow hormetic dosing principles (see Neurohacker Dosing Principles), which means that beyond a certain dose, there may be no additional functional benefits gained (and sometimes there can be lesser benefits at higher doses compared with lower doses). We expect Sea Buckthorn fruit extract to be complementary with other fruit extracts in our formulation, and selected the dose based on it being part of a super fruit blend.* 


SEA BUCKTHORN KEY MECHANISMS


Skin health* 

Influences melanin synthesis [1]

Supports healthy immune/cytokine signaling [2]

Supports skin in adapting to environmental stress [3]

Supports healthy skin structure [3]

Supports skin hydration [3]

Supports healthy transepidermal water loss (TEWL) [3]

Supports healthy extracellular matrix structure [3]

Supports antioxidant defenses [3]


Other*

Supports stem cell mobilization [4]

Supports free radical scavenging [5]

Supports maintenance of healthy body fat levels [6]

Supports healthy gut microbiota [7,8]


Complementary ingredients*

With blueberry in supporting skin health [3]


REFERENCES

[1]J. Zhang, C. Wang, C. Wang, B. Sun, C. Qi, Food Funct. 9 (2018) 5402–5416.

[2]D.-J. Kwon, Y.-S. Bae, S.M. Ju, A.R. Goh, S.Y. Choi, J. Park, Biochem. Biophys. Res. Commun. 409 (2011) 780–785.

[3]I.S. Hwang, J.E. Kim, S.I. Choi, H.R. Lee, Y.J. Lee, M.J. Jang, H.J. Son, H.S. Lee, C.H. Oh, B.H. Kim, S.H. Lee, D.Y. Hwang, Int. J. Mol. Med. 30 (2012) 392–400.

[4]C. Drapeau, K.F. Benson, G.S. Jensen, Clin. Interv. Aging 14 (2019) 253–263.

[5]C. Papuc, C. Diaconescu, V. Nicorescu, Rom. Biotechnol. Lett. 13 (2008) 4049–4053.

[6]H.-M. Lehtonen, J.-P. Suomela, R. Tahvonen, B. Yang, M. Venojärvi, J. Viikari, H. Kallio, European Journal of Clinical Nutrition 65 (2011) 394–401.

[7]S. Attri, G. Goel, Food Res. Int. 111 (2018) 314–323.

[8]C. Guo, L. Han, M. Li, L. Yu, Nutrients 12 (2020).