Black Ginger | Black Turmeric | Krachai Dam
Supports healthy aging*
Supports mitochondrial function*
Supports muscle strength and endurance*
Supports antioxidant defenses*
Kaempferia parviflora is found in the upper Northeastern regions of Thailand. Root extracts have a long history of use and a reputation for being a health tonic and energy enhancer (i.e., Thai ginseng). The novel active constituents are a special type of polyphenol called polymethoxyflavonoids. Sirtmax® Kaempferia parviflora root extract is standardized for polymethoxyflavonoid content.*
Sirtmax® has been used in animal and human research studies.
Created by Tokiwa Phytochemicals, a leader in standardized Kaempferia parviflora supplementation.
Highest concentration, full-spectrum root extract, with triple standardization for 5,7-dimethoxyflavone (≥ 4%), 3, 5, 7, 3', 4'-pentamethoxyflavone (≥ 3.5%), and total polymethoxyflavonoids (≥ 15%).
Grown in Thailand & Laos.
Sirtmax® is a registered trademark of Tokiwa Phytochemical Co., Ltd.
We consider Kaempferia parviflora to be in the adaptogenic herb category; following hormetic dosing principles (see Neurohacker Dosing Principles) with a high likelihood of having a hormetic range (i.e., a serving range below and above which results could be poorer). We have selected a serving that is within the studied range in humans.*
Supports mitochondrial structure and function*
Supports transcription factors of mitochondrial biogenesis (PGC-1α, ERRα, NRF1, TFAM)* [1–3]
Supports mitochondrial number* 
Supports ATP production* 
Promotes β-oxidation (fatty acid metabolism) – upregulates PPARγ and PPARδ* [2,4]
Promotes exercise performance*
Supports endurance performance* [1,2,5,6]
Supports post-exercise recovery* 
Supports muscle strength* [5,6]
Supports muscle metabolism* 
Supports healthy metabolic function*
Supports healthy fat accumulation and blood/liver lipid levels* [4,7,8]
Promotes differentiation of brown adipocyte cells* 
Supports UCP1 and thermogenesis of brown adipose tissue* [4,7,8]
Promotes whole-body energy expenditure through activation of brown adipose tissue* [7,9]
Promotes lean body mass* 
Promotes healthy aging and longevity*
Supports neuroprotective functions* 
Counters the production of advanced glycation end-products (AGEs)* 
Promotes healthy cardiovascular NO signaling and vasodilation* [12–15]
Supports antioxidant enzymes* 
Supports AMPK signaling* [2,3]
Supports SIRT-1 signaling* [2,11]
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
K. Toda, S. Hitoe, S. Takeda, H. Shimoda, Heliyon 2 (2016) e00115.
M.-B. Kim, T. Kim, C. Kim, J.-K. Hwang, J. Med. Food 21 (2018) 30–38.
K. Toda, S. Takeda, S. Hitoe, S. Nakamura, H. Matsuda, H. Shimoda, J. Nat. Med. 70 (2016) 163–172.
H. Kobayashi, E. Horiguchi-Babamoto, M. Suzuki, H. Makihara, H. Tomozawa, M. Tsubata, T. Shimada, K. Sugiyama, M. Aburada, J. Nat. Med. 70 (2016) 54–61.
J. Wattanathorn, S. Muchimapura, T. Tong-Un, N. Saenghong, W. Thukhum-Mee, B. Sripanidkulchai, Evid. Based. Complement. Alternat. Med. 2012 (2012) 732816.
K. Promthep, W. Eungpinichpong, B. Sripanidkulchai, U. Chatchawan, Med. Sci. Monit. Basic Res. 21 (2015) 100–108.
T. Shimada, T. Horikawa, Y. Ikeya, H. Matsuo, K. Kinoshita, T. Taguchi, K. Ichinose, K. Takahashi, M. Aburada, Fitoterapia 82 (2011) 1272–1278.
S. Yoshino, M. Kim, R. Awa, H. Kuwahara, Y. Kano, T. Kawada, Food Sci Nutr 2 (2014) 634–637.
M. Matsushita, T. Yoneshiro, S. Aita, T. Kamiya, N. Kusaba, K. Yamaguchi, K. Takagaki, T. Kameya, H. Sugie, M. Saito, J. Nutr. Sci. Vitaminol. 61 (2015) 79–83.
H.-I. Moon, S.-B. Cho, J.-H. Lee, Y.-C. Lee, J.-H. Lee, C.-H. Lee, S.-K. Kim, Phytother. Res. 25 (2011) 1215–1217.
A. Nakata, Y. Koike, H. Matsui, T. Shimadad, M. Aburada, J. Yang, Nat. Prod. Commun. 9 (2014) 1291–1294.
S.K. Wattanapitayakul, M. Suwatronnakorn, L. Chularojmontri, A. Herunsalee, S. Niumsakul, S. Charuchongkolwongse, N. Chansuvanich, J. Ethnopharmacol. 110 (2007) 559–562.
P. Weerateerangkul, S. Palee, K. Chinda, S.C. Chattipakorn, N. Chattipakorn, J. Cardiovasc. Pharmacol. 60 (2012) 299–309.
P. Tep-Areenan, P. Sawasdee, M. Randall, Phytother. Res. 24 (2010) 1520–1525.
P. Tep-areenan, K. Ingkaninan, M.D. Randall, Asian Biomed. 4 (2010) 103–111.