Enhances working memory and alertness*
Supports cognitive function and performance*
Panax quinquefolius is commonly called American ginseng, because it is native to forested regions in North America. It is the same genus as Asian ginseng (Panax ginseng) and prized for many of the same reasons. Both American and Asian ginseng contain similar active constituents called ginsenosides. The ginsenosides are thought to be responsible for many of the adaptogenic (i.e., stress and fatigue support) and health-promoting properties associated with ginseng. While there are many different ginsenosides, the most well characterized include Rb1, Rb2, Rg1, Rc, Rd, and Re. Cereboost™ is a clinically studied and standardized American ginseng root extract. In humans studies, Cereboost™ has enhanced working memory and alertness, while promoting calmness.
Cereboost™ has been used in human clinical studies, where it has enhanced alertness, working memory, and calmness.
Cereboost™ was granted the NutrAward 2010 for the Best New Ingredient of the year.
Cereboost™ is produced by Naturex, an innovator in nutraceutical products in Europe and the United States.
Cereboost™ is standardized for total ginsenoside content (10-12%), and several specific ginsenosides, including Rb1 (4-7%), Rb2 (0.2-1.5%), Rg1 (0.1-0.4%), Rc (0.5-3.5%), Rd (0.9-3.0%), and Re (0.4-3.5%).
Cereboost™ is non-GMO, gluten-free, and vegan.
Cereboost™is a trademark of Naturex.
We consider Panax quinquefolius to be in the adaptogenic herb category; following hormetic dosing principles (see Neurohacker Dosing Principles) with a high likelihood of having a hormetic range (i.e., a dosing range below and above which results could be poorer). We have selected to dose this at an amount that is consistent with the studied amount in the human clinical studies for supporting working memory, alertness, and calmness.*
Supports attention 
Supports working memory [2,3]
Supports learning and memory [4–7]
Promotes calmness 
Supports mood [1,8,9]
Adaptogenic actions (i.e., stress resilience and anti-fatigue) 
Downregulates stress hormone levels / HPA-axis activation [1,8]
Modulates cholinergic neurotransmission [1,4,5,10,11]
Downregulates acetylcholinesterase (AChE) activity 
Upregulates choline acetyltransferase (ChAT) expression 
Upregulates acetylcholine levels 
Modulates dopaminergic neurotransmission [12–15]
Modulates GABAergic neurotransmission [1,8]
Neuroprotective effects [1,4,5,8,10]
Regulates neural cytokine signaling [1,8,10,16]
Protects against glutamate neurotoxicity [10,17]
Supports neurite outgrowth, dendritic spine density, and synaptic plasticity [1,5–7]
Upregulates BDNF signaling [1,7,10,18]
Supports neurogenesis [1,10,18]
Upregulates antioxidant enzymes in the brain (superoxide dismutase [SOD], catalase [CAT], glutathione peroxidase [GPx]) 
Replenishes glutathione (GSH) levels 
Downregulates lipid peroxidation 
Supports healthy cardiometabolic parameters [19–21]
Supports healthy blood glucose levels [22–24]
Supports healthy insulin sensitivity 
Supports fat metabolism 
Supports mitochondrial enzyme complex activities 
Regulates gut cytokine signaling [26–28]
Modulates gut microbiota composition [27,28]
Supports high-intensity endurance performance [29,30]
Protects from exercise-induced muscle damage [29–31]
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