Gynostemma | Southern Ginseng | Jiaogulan
Gynostemma pentaphyllum (Southern Ginseng) is an herb given Ginseng status although not related to Panax Ginseng. Until recently it was a locally-known herb used primarily in mountainous regions of southern China and in northern Vietnam. It is described by the local inhabitants as the "immortality herb,” because people within Guizhou Province, where jiaogulan herbal teas are consumed regularly, are said to have a history of unusual longevity.
A Gynostemma pentaphyllum extract was selected to be standardized to contain 98% gypenosides.
We opted for a standardized extract for two reasons. Gypenosides are thought to be responsible for much of this herb’s functional benefits. And they have been the primary focus of the majority of the research on this plant.
Studies of this extract suggest it supports cellular and metabolic adaptations similar to what might be expected with exercise. *
We consider Gynostemma pentaphyllum to be an herbal adaptogen, which would follow hormetic dosing principles (see Neurohacker Dosing Principles). It contains a category of triterpenoid saponin compounds called gypenosides. These share many structural and functional similarities with the ginsenoside compounds found in well-known ginseng adaptogens. We’d expect this extract to produce an additive or synergistic response when combined with other polyphenol ingredients, based on existing experimental evidence. The dose we’ve selected is within the hormetic range, a dose range we expect will produce positive adaptive responses over time.
Mitochondrial Structure
Mitochondrial Function
Signaling pathways
Exercise performance (ergogenic effect)
Metabolism
Body weight
Antioxidant defenses
Cellular signaling
Brain function
Protection of organs and systems
Gut microbiota
SYNERGIES
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