Rhodiola rosea Root

Rhodiola rosea is a flowering plant with nootropic and adaptogenic effects. Its biologically active compounds can improve memory and focus.

Scientific Name:
Rhodiola rosea

      • Rosavins and salidrosides are its main biologically active compounds[1]
      • Inhibits monoamine oxidase[2]
      • Increases the levels of dopamine, noradrenalin, adrenalin, serotonin, and melatonin[2]
      • Regulates the opioid β-endorphin – improves mood[3]
      • Decreases fatigue, improves motivation and concentration[3]
      • Promotes longevity – neuroprotective against toxins and oxidative stress; increases the production of antioxidant enzymes[4]
      • Modulates neuropeptide Y activity, increasing HSP72 levels – anti-stress effects[5]
      • Enhances neurogenesis and neuronal regeneration – memory enhancement[6 7]

[1] Panossian A, et al (2010). Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine, 17(7):481-93. doi: 10.1016/j.phymed.2010.02.002
[2] van Diermen D, et al (2009). Monoamine oxidase inhibition by Rhodiola rosea L. roots. J Ethnopharmacol, 122(2):397-401. doi: 10.1016/j.jep.2009.01.007
[3] Kelly GS (2001). Rhodiola rosea: a possible plant adaptogen. Altern Med Rev, 6(3):293-302. PMID: 11410073
[4] Qu ZQ, et al (2009). Pretreatment with Rhodiola rosea extract reduces cognitive impairment induced by intracerebroventricular streptozotocin in rats: implication of anti-oxidative and neuroprotective effects. Biomed Environ Sci, 22(4):318-26. doi: 10.1016/S0895-3988(09)60062-3
[5] Panossian A, et al (2012). Adaptogens stimulate neuropeptide y and hsp72 expression and release in neuroglia cells. Front Neurosci, 6:6. doi: 10.3389/fnins.2012.00006
[6] Qu ZQ, et al (2012). Protective effects of a Rhodiola crenulata extract and salidroside on hippocampal neurogenesis against streptozotocin-induced neural injury in the rat. PLoS One, 7(1):e29641. doi: 10.1371/journal.pone.0029641
[7] Sheng QS, et al (2013). Salidroside promotes peripheral nerve regeneration following crush injury to the sciatic nerve in rats. Neuroreport, 24(5):217-23. doi: 10.1097/WNR.0b013e32835eb867