Thiamine | Thiamin
Thiamine (vitamin B1) is part of the B complex—a group of water-soluble vitamins that play important roles in cellular metabolism and energy production. It was the first of the B complex vitamins to be isolated, which is why it’s called B1. Thiamine is on the World Health Organization's List of Essential Medicines, the most effective and safe compounds needed in a health system, because of its essential role in preventing thiamine deficiency disorders. The body concentrates thiamine in metabolically active tissues, including skeletal muscle, heart, brain, liver, and kidneys. But the body only stores a small amount of thiamine (about 20-30 mg), so it needs to be consumed consistently in the diet. Thiamine is involved in many cellular processes. It is essential for the metabolism of sugars, proteins, and fats, and is instrumental in several important processes needed to make cellular energy.
Thiamine is supplied as thiamine HCL (hydrochloride) because oral supplementation with this form of vitamin B1 can rapidly increase blood levels of thiamine .
Thiamine HCl is NON-GMO, gluten-free and vegan.
Thiamine has a wide dosing range that varies from about the daily value amount of 1.2 mg to several hundred milligrams. We consider it to be subject to a dosing threshold (see Neurohacker Dosing Principles), which means, while more might be better within a range, increasing amounts beyond that range is unlikely to add significant additional nutritional or functional benefits for most people. Depending on the goal of a formulation, the dose of thiamine used can vary. If we are using it in combination with the rest of the B-complex family of vitamins to complement this family’s functional activities, especially for energy production, a low-to-modest dose will be used. If we are using thiamine for a more specific purpose—as a nootropic for example—a higher dose may be used.
Cofactor in the pyruvate dehydrogenase complex
Cofactor in the pentose phosphate pathway
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