Collective Insights Blog

Optimizing Female Hormones: An Interview with Dr. Christiane Northrup

Optimizing Female Hormones: An Interview with Dr. Christiane Northrup

Dr. Heather Sandison is joined by women’s health expert, visionary health pioneer, wellness speaker, and New York Times Best-Selling author, Dr. Christiane Northrup. We dive into women’s health and how to balance female hormones. 

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The Benefits of Grounding: An Interview with Clint Ober

The Benefits of Grounding: An Interview with Clint Ober

We are joined by the innovator behind the Grounding Movement and CEO of Earth FX Inc., Clint Ober. He is known for the Earthing movie and the author of Earthing: The Most Important Health Discovery Ever. We dive into the benefits of grounding and how it can help the body relieve inflammation. We go over science around grounding the tools we can use to help us ground effectively. 

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The Science of Longevity: An Interview with Valter Longo, Ph.D.

The Science of Longevity: An Interview with Valter Longo, Ph.D.

There is so much advice on longevity and aging that it can be hard to sort through all of the information. In this podcast transcript we dive into the science-backed approaches for living a longer and healthier life. Valter Longo, Ph.D., has thirty years of experience in longevity and healthy eating, and is one of the world’s experts in the field.

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 How is NAD+ Made? Preiss-Handler Pathway

How is NAD+ Made? Preiss-Handler Pathway

In 1958, Jack Preiss and Philip Handler published a scientific paper describing how NAD+ was made from niacin in three steps.(1) This pathway was later named the Preiss-Handler pathway after the co-discoverers. It describes the enzyme steps needed to convert niacin into the NAD+ molecule.

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How is NAD+ Made? Salvage Pathway

How is NAD+ Made? Salvage Pathway

The salvage pathway is used to produce NAD+ from nicotinamide molecules. Whether the source of the nicotinamide is vitamin B3 (as niacinamide), newer nicotinamides (e.g., nicotinamide riboside [NR], nicotinamide mononucleotide [NMN]), or molecules in food that get broken down during digestion into nicotinamide, the salvage pathway turns them into NAD+ in our tissues.

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How is NAD+ Made? De Novo Synthesis

How is NAD+ Made? De Novo Synthesis

Most organisms have several alternatives for producing the NAD+ molecule. In humans, there are three major NAD+ biosynthesis pathways: the De Novo Pathway, starting from the essential amino acid L-tryptophan; the Preiss-Handler pathway, using niacin (nicotinic acid); and the Salvage Pathway from niacinamide (nicotinamide). In this article, we’ll be covering the De Novo Pathway.

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Anti-Aging Benefits of Intermittent Fasting

Anti-Aging Benefits of Intermittent Fasting

In Silicon Valley, the hub of anti-aging research and funding, countless entrepreneurs and high-profile celebrities use fasting to combat the effects of aging. In Anti-Aging Benefits of Fasting, we will explore the mechanisms that create these fasting benefits. This part is more scientific than the others, but we emphasize only crucial components in an easily digestible format.

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