Collective Insights Blog

Citrus grandis Fruit Extract: Sources And Benefits

Citrus grandis Fruit Extract: Sources And Benefits

Apigenin belongs to the flavone class of polyphenol compounds. It is one of the more common flavones in the diet, found in many fruits and vegetables, including celery and parsley. It’s also found in high amounts in the flowers used to make chamomile tea.

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Calcium β-Hydroxy-β-Methylbutyrate (HMB): Sources And Benefits

Calcium β-Hydroxy-β-Methylbutyrate (HMB): Sources And Benefits

β-Hydroxy-β-Methylbutyrate (HMB) is a metabolite of l-leucine (an essential amino acid). As we get older, muscle size, strength, and performance decline. This can occur even if we continue to exercise. HMB has been used as an ergogenic substance (i.e., something that supports improved sports performance) for more than 20 years, with most of the research focused on supporting muscle performance and helping muscles age better. 

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Rosmarinus officinalis Leaf Extract: Sources And Benefits

Rosmarinus officinalis Leaf Extract: Sources And Benefits

Rosemary is a member of the mint family. Its common name derives from Latin and translates as “dew of the sea,” because it thrives close to the coast in dryer areas throughout the Mediterranean. It was used as a spice and folk medicine by Egyptians, Greeks, and Latin cultures. While rosemary contains a range of health-supporting polyphenols, including carnosol, carnosic acid, and rosmarinic acid, our main interest was in a triterpene in rosemary called ursolic acid, which supports muscle performance.

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Sirtmax® Kaempferia parviflora Root Extract: Sources And Benefits

Sirtmax® Kaempferia parviflora Root Extract: Sources And Benefits

Kaempferia parviflora is found in the upper northeastern regions of Thailand. It is commonly called black ginger, because of the intense purple-black color and similar shape of the roots to ginger. The traditional use has been as a health tonic and energy enhancer leading to it sometimes being called “Thai ginseng.” The novel active constituents are polymethoxyflavonoids polyphenols. 

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Theobroma cacao Seed Extract: Sources And Benefits

Theobroma cacao Seed Extract: Sources And Benefits

Theobroma cacao can be translated as chocolate, food of the gods. This tree is native to the tropical regions of the Americas. The beans are the source of the cocoa used to make chocolate. But this extract is more than simply a pleasure for our tastebuds. Over the past decade chocolate has had a blossoming reputation as being heart healthy. As it turns out, it might also be good for our mitochondrial structure and function.

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What is Vitamin K2? An Exploration of its Benefits

What is Vitamin K2? An Exploration of its Benefits

Vitamin K is a family of structurally similar, fat-soluble vitamins. The two main members of the family are vitamin K1 and K2. Our interest in vitamin K was prompted when looking for compounds that might be able to rescue mitochondrial performance. This led us to source vitamin K2, ultimately as MK-7. 


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Benefits of Niacin & Niacinamide

Benefits of Niacin & Niacinamide

The main role of vitamin B3 is to make NAD molecules. This is important because the NAD molecule sits at the crossroads of mitochondrial energy production (i.e., ATP), cellular repair and signaling, and cellular defenses. Unfortunately, NAD+ levels decrease with age. This is the bad news. The good news is that there are strategies that can be used to make more NAD+. One of these is vitamin B3.

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L-Tryptophan: Sources and Benefits

L-Tryptophan: Sources and Benefits

L-tryptophan is an essential amino acid. This means the body cannot synthesize it: it must be obtained from the diet. It’s been known for decades that L-tryptophan has niacin equivalent activity in the body (i.e., we can make NAD+ molecules from it). L-tryptophan is unique because it’s the only way to build NAD+ that doesn’t start from vitamin B3. It does this by a de novo synthesis pathway, which creates a niacin molecule through a series of biological reactions. So, L-tryptophan’s inclusion would seem to be a natural fit in a formulation that wants to support boosting NAD+

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French Red Grapes Extract: Sources and Benefits

French Red Grapes Extract: Sources and Benefits

BioVin® is a premium quality grape extract made from the juice, seeds, and skins of red grapes grown in France. It's rich in both trans-resveratrol and grape polyphenols.

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Cinnamon: Sources and Benefits

Cinnamon: Sources and Benefits

Cinnamon is one of the world's oldest spices. Along with pepper and ginger, it was a big part of the spice trade between Asia and Europe. Cinnamon trees are native to India, Sri Lanka, Indonesia, and Burma. What we think of as cinnamon comes from the inner bark of several different tree species from the genus Cinnamomum. 

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Ashwagandha: Sources and Benefits

Ashwagandha: Sources and Benefits

Ashwagandha is an Ayurvedic herb often referred to as “Indian ginseng.” Within this system of it was classified as a general tonic and strength promoting. Its uses included infusing energy and vigor in circumstances characterized by exhaustion or a lack of physical energy. 

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Polyphenols: Sources and Benefits

Polyphenols: Sources and Benefits

Dietary polyphenols are a family of plant compounds found in common foods including fruits, vegetables, nuts, chocolate, coffee, and tea. These compounds play important roles in the plant kingdom, protecting plants from infections, pests, UV irradiation from the sun, oxidative stress, and toxic metals and chemicals.

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Online Education: An Exploration of 7 Websites to Fuel Your Mind

Online Education: An Exploration of 7 Websites to Fuel Your Mind

Get ready to fuel your mind with seven of our favorite resources in the form of websites, companies, programs and even apps that should be on your neurohacking radar!

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How is NAD+ Made? Salvage Pathway

How is NAD+ Made? Salvage Pathway

The salvage pathway is used to produce NAD+ from nicotinamide molecules. Whether the source of the nicotinamide is vitamin B3 (as niacinamide), newer nicotinamides (e.g., nicotinamide riboside [NR], nicotinamide mononucleotide [NMN]), or molecules in food that get broken down during digestion into nicotinamide, the salvage pathway turns them into NAD+ in our tissues.

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Nootropics for Energy: How Athletes Use Smart Drugs as Ergogenics

Nootropics for Energy: How Athletes Use Smart Drugs as Ergogenics

In our last article, Nootropics for Athletes, we discussed several ergogenics (a category of supplements that enhance physical performance, stamina, or recovery) and how they can also be used to optimize brain energy and mental performance. Many of those substances, such as creatine, were well-researched because of their effects on the body. The same is true for numerous nootropic supplements, which were designed to optimize mental performance.

In this article we will cover some well-studied nootropics that also have physical enhancing effects. 

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How is NAD+ Made? De Novo Synthesis

How is NAD+ Made? De Novo Synthesis

Key Learning Objectives

  • Start to appreciate why redundancy is important in living systems.
  • Introduce the three pathways used to make NAD+.
  • Discover how L-tryptophan at breakfast influences what happens at night.
  • Learn about how L-tryptophan is used to make NAD+. 
  • Find out which dietary nutrients support making NAD+ from L-tryptophan
  • Understand why preventing a build-up of quinolinic acid (QA) is important.

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Ergogenics: An Exploration of the Benefits of Nootropics for Athletes

Ergogenics: An Exploration of the Benefits of Nootropics for Athletes

In this blog post we will discuss some of the ergogenics commonly considered tools for physical performance and how they may also have nootropic effects as well.

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Fitness Inspiration: 6 Programs to Jump Start Your Fitness Goals

Fitness Inspiration: 6 Programs to Jump Start Your Fitness Goals

Check out these 6 hand-picked fitness programs to provide the inspiration you need to get your body moving.

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Mitochondria: Exploring 5 Lifestyle Habits to Benefit Cell Health

Mitochondria: Exploring 5 Lifestyle Habits to Benefit Cell Health

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. In this article, we explore lifestyle habits that improve mitochondrial health and support healthy aging.

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Mitochondria Health: An Exploration of Temperature and Light Therapy

Mitochondria Health: An Exploration of Temperature and Light Therapy

Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. Here we explore temperature and light therapy to improve mitochondrial health and support healthy aging.

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Stay Motivated to Workout: Understanding Mental Fatigue

Stay Motivated to Workout: Understanding Mental Fatigue

Mental fatigue lies at the core of motivating yourself to hit the gym and to give the extra push in your athletic performance. In Workout Motivation: The Science of the Brain's Role in Exercise we broadly introduced the importance of our mind for exercise performance. The interconnectedness between the brain and body means many markers of physical performance are modulated by our mind.

Here we focus on mental fatigue, introduce you to some of the fatigue models (how scientists believe the brain is operating), explain willpower and self-control and how they interact with workout motivation, and provide actionable tools to help you follow through on a workout program.

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Workout Motivation: The Science of the Brain's Role in Exercise

Workout Motivation: The Science of the Brain's Role in Exercise

It is clear that exercise influences the mind, but can optimizing the mind influence exercise performance? We explore the foundation of optimizing workout motivation. Read on to learn how to identify some of the key mechanisms that modulate athletic performance, the connection between the body and the brain, and how you can get the most from your workout program.

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NAD: Introduction to an Important Healthspan Molecule

NAD: Introduction to an Important Healthspan Molecule

In this article we’ll be covering the “big picture” when it comes to NAD. We’ll be doing a deeper dive on specific topics we introduce in this article in subsequent articles in this series. As you go through this series of articles please keep in mind that, like other molecules in the body, NAD+ is a means to an end. We don’t care about NAD+ on its own; we care about it because of what it allows cells to do. 

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Finding Your Life Path: An Exploration of Dharma

Finding Your Life Path: An Exploration of Dharma

It's that time in January where we need a boost in our New Year's resolutions. At the end of last year, one of our co-founders, Daniel Schmachtenberger, put together a strategy and list of his favorite resources for creating successful New Year’s Resolutions, or better yet, life planning in general. Daniel joins us again in this article to explore his dharma definition and how to use this dharma inquiry to explore your own unique life path.

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Is Fasting Good for You? Q&A on Fasting

Is Fasting Good for You? Q&A on Fasting

In our earlier articles in our guide to fasting series (How to Fast, What to Expect While Intermittent Fasting, and Anti-Aging Benefits) you learned the science behind fasting, the underlying mechanisms that provide benefits, and how to start. In Is Fasting Good for You? Q&A on Fasting we focus on five of the most pressing questions we believe members of the Neurohacker Collective community are interested in learning.

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